Do or Die was released on May 30, 1921
Most of this adventure serial was filmed in Cuba, but a few scenes were filmed on California's Santa Catalina Island. Here's the story: Some members of an American family live in Cuba and own a special ring that contains a map to buried pirate treasure. A guy named Satan is the bad guy. (What else could he be with a name like that?) Satan tries repeatedly to gain possession of the ring.
A member of the family from the United States goes to Cuba to help combat Satan. He finds it's not as easy as it sounds because it takes 18 hellish episodes to combat the forces of evil.